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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA3
All Species:
48.18
Human Site:
Y278
Identified Species:
66.25
UniProt:
P30101
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30101
NP_005304.3
505
56782
Y278
K
N
A
K
G
S
N
Y
W
R
N
R
V
M
M
Chimpanzee
Pan troglodytes
XP_001159528
485
54945
Y258
K
N
A
K
G
S
N
Y
W
R
N
R
V
M
M
Rhesus Macaque
Macaca mulatta
XP_001108948
480
54081
Y253
K
N
A
K
G
S
N
Y
W
R
N
R
V
M
M
Dog
Lupus familis
XP_535453
687
75990
Y460
K
N
A
K
G
S
N
Y
W
R
N
R
V
M
M
Cat
Felis silvestris
Mouse
Mus musculus
P27773
505
56660
Y278
K
N
A
K
G
S
N
Y
W
R
N
R
V
M
M
Rat
Rattus norvegicus
P11598
505
56605
Y278
K
N
T
K
G
S
N
Y
W
R
N
R
V
M
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517928
483
54617
Y255
K
N
A
K
G
S
N
Y
W
R
N
R
V
M
M
Chicken
Gallus gallus
Q8JG64
505
56163
Y276
K
N
A
K
G
S
N
Y
W
R
N
R
V
M
M
Frog
Xenopus laevis
NP_001080051
502
56103
Y275
K
N
V
K
G
T
N
Y
W
R
N
R
V
M
K
Zebra Danio
Brachydanio rerio
NP_998070
488
54656
Y269
R
N
P
K
G
T
N
Y
W
R
N
R
I
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K276
E
K
Y
V
D
P
L
K
E
I
A
K
K
Y
R
Honey Bee
Apis mellifera
XP_623282
490
55838
Y270
K
N
P
K
G
T
N
Y
W
R
N
R
I
I
K
Nematode Worm
Caenorhab. elegans
P34329
618
69779
Y402
Q
Y
R
E
G
S
E
Y
W
R
S
K
V
L
N
Sea Urchin
Strong. purpuratus
XP_782981
472
51996
V267
L
D
K
K
V
M
N
V
G
R
E
F
I
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
S287
F
S
T
G
P
F
D
S
F
K
S
A
Y
S
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
K283
G
A
T
A
E
A
L
K
S
K
Y
R
E
V
A
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
G286
E
L
A
K
K
N
R
G
L
M
N
F
V
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
94.4
70.8
N.A.
93
92.2
N.A.
84.7
80.9
74.6
60
N.A.
32.6
49.5
36.7
50.5
Protein Similarity:
100
92.6
94.8
72.1
N.A.
97
96.2
N.A.
90.3
90.8
88.3
77.2
N.A.
53.4
63.7
50.4
65.9
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
80
66.6
N.A.
0
66.6
40
20
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
86.6
86.6
N.A.
13.3
86.6
73.3
33.3
Percent
Protein Identity:
N.A.
34.3
N.A.
35.6
26.8
N.A.
Protein Similarity:
N.A.
51
N.A.
54.9
48.4
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
48
6
0
6
0
0
0
0
6
6
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
6
0
6
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
6
6
0
6
0
6
0
6
0
6
0
0
% E
% Phe:
6
0
0
0
0
6
0
0
6
0
0
12
0
0
0
% F
% Gly:
6
0
0
6
71
0
0
6
6
0
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
6
0
0
18
6
6
% I
% Lys:
59
6
6
77
6
0
0
12
0
12
0
12
6
0
18
% K
% Leu:
6
6
0
0
0
0
12
0
6
0
0
0
0
6
0
% L
% Met:
0
0
0
0
0
6
0
0
0
6
0
0
0
59
48
% M
% Asn:
0
65
0
0
0
6
71
0
0
0
71
0
0
0
6
% N
% Pro:
0
0
12
0
6
6
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
6
0
6
0
0
0
6
0
0
77
0
71
0
0
6
% R
% Ser:
0
6
0
0
0
53
0
6
6
0
12
0
0
12
6
% S
% Thr:
0
0
18
0
0
18
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
6
6
6
0
0
6
0
0
0
0
65
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
71
0
0
0
0
0
0
% W
% Tyr:
0
6
6
0
0
0
0
71
0
0
6
0
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _